NEWS

DC Granules for more than just Tableting

The DC Granules product line by Dr. Paul Lohmann® covers Calcium, Magnesium, Iron and Zinc Salts offering lots of application benefits.

The granulation process enlarges the particle size by converting fine or coarse powders into physically strong and larger granules with uniform shape, good flow property as well as good compression characteristics.

Granules are formed by adding a liquid solution (water with or without binding agent) to powders. Binding agents of the product line are maltodextrin, starch, PVP, citric acid and gum arabic. From a production point of view, DC (direct compressible) grades offer excellent tableting properties. Granulated DC grades solve challenges during the tableting process due to the physical modification. Tablet manufacturers usually use wet granulation of powders prior to the tableting process to improve the compactability and flowability of a tablet formulation. The use of directly compressable granulated Minerals for the tableting process eliminates the need of an in-house granulation process, and offers vast advantages in terms of production capability and cost.

Vital Immune System in the Days of SARS-CoV-2

The maintenance of the immune system is gaining more importance within the last weeks and months. Nutrition plays an important role relating to this topic. A sufficient supply with micronutrients is essential for health and wellbeing. Even minor deficiencies in some micronutrients may lead to a decreased immune response. Some Minerals are known in particular to support the immune system. Zinc is one of the most famous Minerals for the human health besides Iron, Copper and Selenium.

Common cold starts with an infection with rhinoviruses. This kind of virus accounts for 30 % to 50 %, in autumn even up to 80 % of all upper respiratory infections. Corona viruses cause 10 % to 15 % of upper respiratory infections.

Zinc shortens the duration of a common cold effectively when administered within an early period of the illness, approx. 24 hours after the onset of symptoms. Taking Zinc containing food supplements should be continued until symptoms resolve. Zinc is well described for its anti-microbial effect, which is of importance for pneumonia resulting from bacterial super infection of the lungs after viral infection. Moreover, there are studies indicating anti-viral properties of Zinc. By acting as a competitive inhibitor Zinc prevents rhinoviruses to enter into the upper respiratory tract.   

The right choice of the Zinc compound is of particular importance. Free Zn2+ Ions have a better effectiveness compared to insoluble Zinc Salts. The ionic availability of Zinc is a challenge in the product development process. Most of the soluble Zinc Salts have a metallic and astringent taste. Taste masking and flavoring may influence the performance of Zinc.

Zinc Ascorbate by Dr. Paul Lohmann® as a fully reacted mineral is the perfect combination of two major players for the immune system: Zinc and Vitamine C. It is a free-flowing powder with a good solubility in water. Another positive effect is the pleasant taste of this high value Mineral Salt.

Further highly suitable and recommended Zinc Salts are Zinc Gluconate, Zinc Sulfate, Zinc Acetate and Zinc Bisglycinate. Zinc Bisglycinate contains the amino acid glycine and is characterized by its excellent bioavailability.

 

References:

Hulisz, D. (2004). Efficacy of zinc against common cold viruses: an overview. Journal of the American Pharmacists Association, 44(5), 594-603.

Fluhr, J.W., Bösch, B., Gloor, M.M., & Höffler, U. (1999). In-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. Zentralblatt fur Bakteriologie: International journal of medical microbiology

Disinfectant from Emmerthal for Sana clinics

In consideration of the COVID-19 pandemic the supply of disinfectant to hospitals is of crucial importance. To ensure the demand at all Sana Hospitals nationally, the Hospital Group has entered a cooperation with Dr. Paul Lohmann®. Dr. Paul Lohmann® provides 27,000 litres in 25l canister of disinfectant to the Sana Group. With the disinfectant provided, all 55 hospitals of the Sana Group can be fully supplied for two months.

The production of disinfectants is not the core business of our company but the necessary raw materials, the technical requirements and the know-how for the production were available. Therefore, we were happy to support the Sana Group during this extraordinary time.

Food Supplements for Vegetarian and Vegan Nutrition

The vegetarian and vegan lifestyle has become more and more important in recent years.
But this form of nutrition is not without risk. Enriching vegetarian and vegan foods with Minerals can help to minimize the risk of mineral deficiency.

Animal products often have higher contents of various Minerals. These amounts are difficult to achieve with a purely vegetable diet. Calcium, for example, is found in many plant-based foods only in low concentrations. The daily requirement of Calcium (1000 mg/day for adults) is therefore difficult to cover. Iron is present in plant foods as Fe3+, which is difficult to absorb. In contrast, iron is more easily absorbed by the body as Fe2+ from meat. The same applies to Zinc, which can be better absorbed from animal products such as meat or fish.

In addition, besides the low mineral content, the absorption of Minerals such as Calcium, Iron and Zinc is also inhibited by various components of plant foods, for example by dietary fibres, oxalic acid or phytic acid.

Vegetarian or vegan meat and milk substitute products enriched with Minerals offer a good possibility of a balanced mineral supply. Meat substitutes based on soya or other vegetable proteins are highly processed products that are ideally suited for enrichment with Minerals during the manufacturing process. They represent a diverse matrix which can be refined as needed.

According to the Health Claims Regulation (EC) No. 1924/2006, highly enriched foods can be labelled with a health claim for the corresponding Mineral. This makes it easier for the consumer to identify foods with added health value.

The regular intake of food supplements as part of the normal diet can also ensure a sufficient supply of Minerals even if animal products are completely avoided.

 

Our Fortification Recommendation:

Fortification Recommendation

New Iron API

Dr. Paul Lohmann® has recently developed Iron(III) Polymaltose Complex and Iron(II) Bisglycinate as active pharmaceutical ingredients. These products are available including API documentation (DMF/ASMF) for the registration of a medicinal drug at the health authorities.

 

Iron(III) Polymaltose Complex and Iron(II) Bisglycinate are mainly used to treat iron deficiency anemia.1, 2 Both Iron APIs are known for their high bioavailability and have the advantage of high patient compliance due to less side effects related to the upper gastro intestinal tract.1,3 Moreover, there are studies indicating the application of Iron(III) Polymaltose Complex as a phosphate binder to treat hyperphosphatemia.4

 

References
1 Tobli and Brignoli, 2007
2 Name et al., 2018
3 Ferrari et al., 2012
4 Schouten et al., 2009

Milch gießen

Superfine Tricalcium Citrate 4-hydrate for Super Fine Results in Milk

With the newly developed Tricalcium Citrate 4-hydrate superfine, Dr. Paul Lohmann® found the answer to a high demand on a Calcium Citrate with a sharply reduced speed of sedimentation in dairy and plant milk products. With the help of this superfine powder, customers will be able to fortify their dairy products with Calcium with a significant reduction of sedimentation during the production process.

The Research and Development department at Dr. Paul Lohmann® did a lot of application trials with Tricalcium Citrate 4-hydrate with different particle sizes like normal powder, micronized powder, fine powder and superfine powder. The products were tested on their performance in different kinds of dairy products, e.g. milk (1.5 % fat and 3.5 % fat), cream and oat milk. The test results showed that the superfine powder was the best performing product within this series of tests, with the slowest sedimentation velocity and the smallest amount of sediment at the bottom of the testing tubes. Another positive effect is the improvement of taste and mouth feeling by using the superfine powder.

DC Granules for more than just Tableting

The DC Granules product line by Dr. Paul Lohmann® covers Calcium, Magnesium, Iron and Zinc Salts offering lots of application benefits.

The granulation process enlarges the particle size by converting fine or coarse powders into physically strong and larger granules with uniform shape, good flow property as well as good compression characteristics.

Granules are formed by adding a liquid solution (water with or without binding agent) to powders. Binding agents of the product line are maltodextrin, starch, PVP, citric acid and gum arabic. From a production point of view, DC (direct compressible) grades offer excellent tableting properties. Granulated DC grades solve challenges during the tableting process due to the physical modification. Tablet manufacturers usually use wet granulation of powders prior to the tableting process to improve the compactability and flowability of a tablet formulation. The use of directly compressable granulated Minerals for the tableting process eliminates the need of an in-house granulation process, and offers vast advantages in terms of production capability and cost.

Vital Immune System in the Days of SARS-CoV-2

The maintenance of the immune system is gaining more importance within the last weeks and months. Nutrition plays an important role relating to this topic. A sufficient supply with micronutrients is essential for health and wellbeing. Even minor deficiencies in some micronutrients may lead to a decreased immune response. Some Minerals are known in particular to support the immune system. Zinc is one of the most famous Minerals for the human health besides Iron, Copper and Selenium.

Common cold starts with an infection with rhinoviruses. This kind of virus accounts for 30 % to 50 %, in autumn even up to 80 % of all upper respiratory infections. Corona viruses cause 10 % to 15 % of upper respiratory infections.

Zinc shortens the duration of a common cold effectively when administered within an early period of the illness, approx. 24 hours after the onset of symptoms. Taking Zinc containing food supplements should be continued until symptoms resolve. Zinc is well described for its anti-microbial effect, which is of importance for pneumonia resulting from bacterial super infection of the lungs after viral infection. Moreover, there are studies indicating anti-viral properties of Zinc. By acting as a competitive inhibitor Zinc prevents rhinoviruses to enter into the upper respiratory tract.   

The right choice of the Zinc compound is of particular importance. Free Zn2+ Ions have a better effectiveness compared to insoluble Zinc Salts. The ionic availability of Zinc is a challenge in the product development process. Most of the soluble Zinc Salts have a metallic and astringent taste. Taste masking and flavoring may influence the performance of Zinc.

Zinc Ascorbate by Dr. Paul Lohmann® as a fully reacted mineral is the perfect combination of two major players for the immune system: Zinc and Vitamine C. It is a free-flowing powder with a good solubility in water. Another positive effect is the pleasant taste of this high value Mineral Salt.

Further highly suitable and recommended Zinc Salts are Zinc Gluconate, Zinc Sulfate, Zinc Acetate and Zinc Bisglycinate. Zinc Bisglycinate contains the amino acid glycine and is characterized by its excellent bioavailability.

 

References:

Hulisz, D. (2004). Efficacy of zinc against common cold viruses: an overview. Journal of the American Pharmacists Association, 44(5), 594-603.

Fluhr, J.W., Bösch, B., Gloor, M.M., & Höffler, U. (1999). In-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. Zentralblatt fur Bakteriologie: International journal of medical microbiology

Disinfectant from Emmerthal for Sana clinics

In consideration of the COVID-19 pandemic the supply of disinfectant to hospitals is of crucial importance. To ensure the demand at all Sana Hospitals nationally, the Hospital Group has entered a cooperation with Dr. Paul Lohmann®. Dr. Paul Lohmann® provides 27,000 litres in 25l canister of disinfectant to the Sana Group. With the disinfectant provided, all 55 hospitals of the Sana Group can be fully supplied for two months.

The production of disinfectants is not the core business of our company but the necessary raw materials, the technical requirements and the know-how for the production were available. Therefore, we were happy to support the Sana Group during this extraordinary time.

Food Supplements for Vegetarian and Vegan Nutrition

The vegetarian and vegan lifestyle has become more and more important in recent years.
But this form of nutrition is not without risk. Enriching vegetarian and vegan foods with Minerals can help to minimize the risk of mineral deficiency.

Animal products often have higher contents of various Minerals. These amounts are difficult to achieve with a purely vegetable diet. Calcium, for example, is found in many plant-based foods only in low concentrations. The daily requirement of Calcium (1000 mg/day for adults) is therefore difficult to cover. Iron is present in plant foods as Fe3+, which is difficult to absorb. In contrast, iron is more easily absorbed by the body as Fe2+ from meat. The same applies to Zinc, which can be better absorbed from animal products such as meat or fish.

In addition, besides the low mineral content, the absorption of Minerals such as Calcium, Iron and Zinc is also inhibited by various components of plant foods, for example by dietary fibres, oxalic acid or phytic acid.

Vegetarian or vegan meat and milk substitute products enriched with Minerals offer a good possibility of a balanced mineral supply. Meat substitutes based on soya or other vegetable proteins are highly processed products that are ideally suited for enrichment with Minerals during the manufacturing process. They represent a diverse matrix which can be refined as needed.

According to the Health Claims Regulation (EC) No. 1924/2006, highly enriched foods can be labelled with a health claim for the corresponding Mineral. This makes it easier for the consumer to identify foods with added health value.

The regular intake of food supplements as part of the normal diet can also ensure a sufficient supply of Minerals even if animal products are completely avoided.

 

Our Fortification Recommendation:

Fortification Recommendation

New Iron API

Dr. Paul Lohmann® has recently developed Iron(III) Polymaltose Complex and Iron(II) Bisglycinate as active pharmaceutical ingredients. These products are available including API documentation (DMF/ASMF) for the registration of a medicinal drug at the health authorities.

 

Iron(III) Polymaltose Complex and Iron(II) Bisglycinate are mainly used to treat iron deficiency anemia.1, 2 Both Iron APIs are known for their high bioavailability and have the advantage of high patient compliance due to less side effects related to the upper gastro intestinal tract.1,3 Moreover, there are studies indicating the application of Iron(III) Polymaltose Complex as a phosphate binder to treat hyperphosphatemia.4

 

References
1 Tobli and Brignoli, 2007
2 Name et al., 2018
3 Ferrari et al., 2012
4 Schouten et al., 2009

Milch gießen

Superfine Tricalcium Citrate 4-hydrate for Super Fine Results in Milk

With the newly developed Tricalcium Citrate 4-hydrate superfine, Dr. Paul Lohmann® found the answer to a high demand on a Calcium Citrate with a sharply reduced speed of sedimentation in dairy and plant milk products. With the help of this superfine powder, customers will be able to fortify their dairy products with Calcium with a significant reduction of sedimentation during the production process.

The Research and Development department at Dr. Paul Lohmann® did a lot of application trials with Tricalcium Citrate 4-hydrate with different particle sizes like normal powder, micronized powder, fine powder and superfine powder. The products were tested on their performance in different kinds of dairy products, e.g. milk (1.5 % fat and 3.5 % fat), cream and oat milk. The test results showed that the superfine powder was the best performing product within this series of tests, with the slowest sedimentation velocity and the smallest amount of sediment at the bottom of the testing tubes. Another positive effect is the improvement of taste and mouth feeling by using the superfine powder.

DC Granules for more than just Tableting

The DC Granules product line by Dr. Paul Lohmann® covers Calcium, Magnesium, Iron and Zinc Salts offering lots of application benefits.

The granulation process enlarges the particle size by converting fine or coarse powders into physically strong and larger granules with uniform shape, good flow property as well as good compression characteristics.

Granules are formed by adding a liquid solution (water with or without binding agent) to powders. Binding agents of the product line are maltodextrin, starch, PVP, citric acid and gum arabic. From a production point of view, DC (direct compressible) grades offer excellent tableting properties. Granulated DC grades solve challenges during the tableting process due to the physical modification. Tablet manufacturers usually use wet granulation of powders prior to the tableting process to improve the compactability and flowability of a tablet formulation. The use of directly compressable granulated Minerals for the tableting process eliminates the need of an in-house granulation process, and offers vast advantages in terms of production capability and cost.

Vital Immune System in the Days of SARS-CoV-2

The maintenance of the immune system is gaining more importance within the last weeks and months. Nutrition plays an important role relating to this topic. A sufficient supply with micronutrients is essential for health and wellbeing. Even minor deficiencies in some micronutrients may lead to a decreased immune response. Some Minerals are known in particular to support the immune system. Zinc is one of the most famous Minerals for the human health besides Iron, Copper and Selenium.

Common cold starts with an infection with rhinoviruses. This kind of virus accounts for 30 % to 50 %, in autumn even up to 80 % of all upper respiratory infections. Corona viruses cause 10 % to 15 % of upper respiratory infections.

Zinc shortens the duration of a common cold effectively when administered within an early period of the illness, approx. 24 hours after the onset of symptoms. Taking Zinc containing food supplements should be continued until symptoms resolve. Zinc is well described for its anti-microbial effect, which is of importance for pneumonia resulting from bacterial super infection of the lungs after viral infection. Moreover, there are studies indicating anti-viral properties of Zinc. By acting as a competitive inhibitor Zinc prevents rhinoviruses to enter into the upper respiratory tract.   

The right choice of the Zinc compound is of particular importance. Free Zn2+ Ions have a better effectiveness compared to insoluble Zinc Salts. The ionic availability of Zinc is a challenge in the product development process. Most of the soluble Zinc Salts have a metallic and astringent taste. Taste masking and flavoring may influence the performance of Zinc.

Zinc Ascorbate by Dr. Paul Lohmann® as a fully reacted mineral is the perfect combination of two major players for the immune system: Zinc and Vitamine C. It is a free-flowing powder with a good solubility in water. Another positive effect is the pleasant taste of this high value Mineral Salt.

Further highly suitable and recommended Zinc Salts are Zinc Gluconate, Zinc Sulfate, Zinc Acetate and Zinc Bisglycinate. Zinc Bisglycinate contains the amino acid glycine and is characterized by its excellent bioavailability.

 

References:

Hulisz, D. (2004). Efficacy of zinc against common cold viruses: an overview. Journal of the American Pharmacists Association, 44(5), 594-603.

Fluhr, J.W., Bösch, B., Gloor, M.M., & Höffler, U. (1999). In-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. Zentralblatt fur Bakteriologie: International journal of medical microbiology

Disinfectant from Emmerthal for Sana clinics

In consideration of the COVID-19 pandemic the supply of disinfectant to hospitals is of crucial importance. To ensure the demand at all Sana Hospitals nationally, the Hospital Group has entered a cooperation with Dr. Paul Lohmann®. Dr. Paul Lohmann® provides 27,000 litres in 25l canister of disinfectant to the Sana Group. With the disinfectant provided, all 55 hospitals of the Sana Group can be fully supplied for two months.

The production of disinfectants is not the core business of our company but the necessary raw materials, the technical requirements and the know-how for the production were available. Therefore, we were happy to support the Sana Group during this extraordinary time.

Food Supplements for Vegetarian and Vegan Nutrition

The vegetarian and vegan lifestyle has become more and more important in recent years.
But this form of nutrition is not without risk. Enriching vegetarian and vegan foods with Minerals can help to minimize the risk of mineral deficiency.

Animal products often have higher contents of various Minerals. These amounts are difficult to achieve with a purely vegetable diet. Calcium, for example, is found in many plant-based foods only in low concentrations. The daily requirement of Calcium (1000 mg/day for adults) is therefore difficult to cover. Iron is present in plant foods as Fe3+, which is difficult to absorb. In contrast, iron is more easily absorbed by the body as Fe2+ from meat. The same applies to Zinc, which can be better absorbed from animal products such as meat or fish.

In addition, besides the low mineral content, the absorption of Minerals such as Calcium, Iron and Zinc is also inhibited by various components of plant foods, for example by dietary fibres, oxalic acid or phytic acid.

Vegetarian or vegan meat and milk substitute products enriched with Minerals offer a good possibility of a balanced mineral supply. Meat substitutes based on soya or other vegetable proteins are highly processed products that are ideally suited for enrichment with Minerals during the manufacturing process. They represent a diverse matrix which can be refined as needed.

According to the Health Claims Regulation (EC) No. 1924/2006, highly enriched foods can be labelled with a health claim for the corresponding Mineral. This makes it easier for the consumer to identify foods with added health value.

The regular intake of food supplements as part of the normal diet can also ensure a sufficient supply of Minerals even if animal products are completely avoided.

 

Our Fortification Recommendation:

Fortification Recommendation

New Iron API

Dr. Paul Lohmann® has recently developed Iron(III) Polymaltose Complex and Iron(II) Bisglycinate as active pharmaceutical ingredients. These products are available including API documentation (DMF/ASMF) for the registration of a medicinal drug at the health authorities.

 

Iron(III) Polymaltose Complex and Iron(II) Bisglycinate are mainly used to treat iron deficiency anemia.1, 2 Both Iron APIs are known for their high bioavailability and have the advantage of high patient compliance due to less side effects related to the upper gastro intestinal tract.1,3 Moreover, there are studies indicating the application of Iron(III) Polymaltose Complex as a phosphate binder to treat hyperphosphatemia.4

 

References
1 Tobli and Brignoli, 2007
2 Name et al., 2018
3 Ferrari et al., 2012
4 Schouten et al., 2009

Milch gießen

Superfine Tricalcium Citrate 4-hydrate for Super Fine Results in Milk

With the newly developed Tricalcium Citrate 4-hydrate superfine, Dr. Paul Lohmann® found the answer to a high demand on a Calcium Citrate with a sharply reduced speed of sedimentation in dairy and plant milk products. With the help of this superfine powder, customers will be able to fortify their dairy products with Calcium with a significant reduction of sedimentation during the production process.

The Research and Development department at Dr. Paul Lohmann® did a lot of application trials with Tricalcium Citrate 4-hydrate with different particle sizes like normal powder, micronized powder, fine powder and superfine powder. The products were tested on their performance in different kinds of dairy products, e.g. milk (1.5 % fat and 3.5 % fat), cream and oat milk. The test results showed that the superfine powder was the best performing product within this series of tests, with the slowest sedimentation velocity and the smallest amount of sediment at the bottom of the testing tubes. Another positive effect is the improvement of taste and mouth feeling by using the superfine powder.

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